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LPS increases the expression of cleaved caspase-3 in AMs from the mouse silicosis model. (a) Mouse AMs from groups treated with sterile saline, silica, and silica + LPS were analyzed for cleaved caspase-3 expression by western blotting; β-actin was used as a loading control. (b) Cleaved caspase-3/β-actin for each group. Significance was determined using one-way ANOVA (n = 6 for each group. *P < 0.05 vs control; # P < 0.05 vs silica).
