Fig 1.

Individual ROC curves of serum GPBB, Mb, and BNP as well as ROC curves of GPBB, Mb and BNP in combination in the diagnosis of AIC, AUC increase with the diagnostic accuracy. As shown in the figure, the area under the ROC curve of GPBB + Mb + BNP is the largest, suggesting that the combination of the three parameters has the highest diagnostic accuracy. ROC curve, Receiver Operating Characteristic curve; GPBB, lycogen phosphorylase isoenzyme BB; Mb, myoglobin; BNP, brain natriuretic peptide; AIC, anthracycline-induced cardiotoxicity; AUC, area under the curve.