Table 4.
Before chemotherapy | p | After chemotherapy | p | |
---|---|---|---|---|
LVEF(%) | ||||
Normal heart group | 56.29 ± 5.14 | 0.844 | 53.99 ± 6.85* | 0.009 |
Cardiotoxicity group | 56.51 ± 6.27 | 50.63 ± 4.77* | ||
E/A | ||||
Normal heart group | 1.27 ± 0.34 | 0.891 | 1.14 ± 0.03* | < 0.001 |
Cardiotoxicity group | 1.26 ± 0.27 | 1.03 ± 0.04* | ||
EDT/ms | ||||
Normal heart group | 174.23 ± 35.15 | 0.509 | 187.65 ± 22.90* | 0.001 |
Cardiotoxicity group | 169.37 ± 37.38 | 204.39 ± 29.84* | ||
IVRT/ms | ||||
Normal heart group | 82.17 ± 10.23 | 0.774 | 70.46 ± 16.34* | 0.011 |
Cardiotoxicity group | 81.53 ± 12.56 | 61.86 ± 17.86* |
Note: LVEF, left ventricular ejection fraction; E/A, mitral ratio of peak early to late diastolic filling velocity; IVRT, isovolumic relaxation time; EDT, E-wave deceleration time. * refers to p < 0.05 vs values of echocardiogram indexes in study population before chemotherapy.