Table 2A.
NRS scores by group for pain pre- and post-HUT and after 24 h, 48 h, and 7 days.
|
Group 1 HC |
Group 2 ME/CFS FM- |
Group 3 with ME/CFS FM+ |
Kruskal–Wallis test with Dunn's multiple comparisons test | |
|---|---|---|---|---|
| NRS for pain pre-HUT | 0 (0–1) | 3 (1–5) | 5 (3–6) | X2(2) = 68.75; p < 0.0001. Post hoc tests: 1 vs. 2 p < 0.0001; 1 vs. 3 p < 0.0001 and 2 vs. 3 p < 0.0001 |
| NRS for pain post-HUT | 0 (0–1) | 4 (2–6) | 6 (4–8) | X2(2) = 79.39; p < 0.0001. Post hoc tests: 1 vs. 2 p < 0.0001; 1 vs. 3 p < 0.0001 and 2 vs. 3 p < 0.0001 |
| NRS for pain 24 h | 0 (0–1) | 6 (3–7) | 7 (6–8) | X2(2) = 85.23; p < 0.0001. Post hoc tests: 1 vs. 2 p < 0.0001; 1 vs. 3 p < 0.0001 and 2 vs. 3 p < 0.0001 |
| NRS for pain 48 h | 0 (0–1) | 5 (3–7) | 7 (5.8–8) | X2(2) = 90.55; p < 0.0001. Post hoc tests: 1 vs. 2 p < 0.0001; 1 vs. 3 p < 0.0001 and 2 vs. 3 p < 0.0001 |
| NRS for pain 7 days | 0 (0–1) | 5 (3–7) | 7 (5–8) | X2(2) = 81.04; p < 0.0001. Post hoc tests: 1 vs. 2 p < 0.0001; 1 vs. 3 p < 0.0001 and 2 vs. 3 p < 0.0001 |
FM, fibromyalgia; HC, healthy controls; HUT, head-up tilt test; NRS, numeric rating scale. With equal skews a mixed two-way ANOVA could be performed analyzing both patient groups (without FM and with FM) and all five in subject variables (pre-HUT, post-HUT, after 24 h, after 48 h and after 7 days) on pain: F (4, 1375)= 0.21; p = 0.93.