Table 2.
A alleles at rs5498 of ICAM-1 and rs3181092 of VCAM-1 is associated with increased risk for PD: n (%)
| Genotype | PD group | Control group | p | OR value (95% CI) |
|---|---|---|---|---|
| (n = 98) | (n = 96) | |||
| 5498A/G | ||||
| AA | 84 (42.86) | 65 (33.85) | Ref. | |
| AG | 86 (43.88) | 89 (46.35) | 0.193 | 1.337 (0.862 - 2.075) |
| GG | 26 (13.26) | 38 (19.80) | 0.035 | 0.529 (0.292 - 0.959) |
| AG + GG | 112 (57.13) | 127 (66.15) | 0.068 | 0.682 (0.452 - 1.030) |
| A allele | 254 (64.80) | 219 (57.03) | Ref. | |
| G allele | 138 (35.20) | 165 (42.97) | 0.026 | 0.721 (0.539 - 0.963) |
| 3181092A/G | ||||
| AA | 72 (36.73) | 40 (20.83) | Ref. | |
| AG | 98 (50.00) | 97 (50.52) | 0.017 | 0.561 (0.348 - 0.905) |
| GG | 26 (13.27) | 55 (28.65) | 0.001 | 0.263 (0.143 - 0.481) |
| AG + GG | 124 (63.27) | 152 (79.17) | 0.001 | 0.453 (0.288 - 0.713) |
| A allele | 242 (61.73) | 177 (46.09) | Ref. | |
| G allele | 150 (38.27) | 207 (53.91) | 0.001 | 0.530 (0.398 - 0.705) |
Notes: OR = odds ratio; CI = confidence intervals; ICAM-1 = intercellular adhesion molecule-1; VCAM-1 = vascular cell adhesion molecule-1; PD = periodontal disease.