Table 3.
AA genotypes of rs5498 and rs3181092 of ICAM-1 and VCAM-1 genes is associated with increase of BI index, CAL and the severity of PD
| Clinical features | rs5498 |
P | rs3181092 |
P | ||
|---|---|---|---|---|---|---|
| AA | AG + GG | AA | AG + GG | |||
| PI | 0.97 ± 0.15 | 0.94 ± 0.16 | 0.183 | 0.965 ± 0.15 | 0.95 ± 0.16 | 0.667 |
| BI | 3.18 ± 0.55 | 2.83 ± 0.40 | 0.001 | 3.11 ± 0.54 | 2.91 ± 0.47 | 0.007 |
| Probing depth (mm) | 2.88 ± 0.36 | 2.85 ± 0.28 | 0.512 | 2.83 ± 0.38 | 2.82 ± 0.28 | 0.833 |
| CAL (mm) | 3.15 ± 0.84 | 2.85 ± 1.04 | 0.001 | 3.85 ± 0.33 | 2.48 ± 0.86 | 0.001 |
| Severity | ||||||
| Mild | 18 (21.43) | 63 (56.25) | 27 (37.50) | 54 (43.55) | ||
| Medium | 25 (29.76) | 35 (31.25) | 0.001 | 17 (23.61) | 43 (34.68) | 0.030 |
| Severe | 41 (48.81) | 14 (12.50) | 28 (38.89) | 27 (21.77) | ||
Notes: PI = plaque index; BI = bleeding index; CAL = clinical attachment level; PD = periodontal disease; ICAM-1 = intercellular adhesion molecule-1; VCAM-1 = vascular cell adhesion molecule-1.