Figure 5.

Co-downregulation of GRP78 and GRP94 affects the expression of apoptosis- and migration-related proteins in PCa cells. A: 48 hours after transfection, protein expression levels of caspase-9, Bcl-2, Bax and vimentin were evaluated in PC-3 cells in the blank, NC and siGRP78+94 groups. B: Relative expression levels of the four proteins examined in panel A. Protein expression was assessed in three experimental groups and was calculated relative to the blank group. * indicates P<0.01 compared to the NC group.