Table 3.
Demographic data, clinical characteristics and inflammatory parameters referring to the disease subtype and skin involvement in limited cutaneous SSc and diffuse cutaneous SSc, respectively (lcSSc and dcSSc)
| Parameter | lcSSc (n = 15) | dcSSc (n = 7) | P-value |
|---|---|---|---|
| Age, mean ± SD [years] | 54.93 ±9.32 | 47.86 ±11.32 | 0.14 |
| Females, n (%) | 14 (93.33) | 7 (100) | 0.69 |
| BMI, mean ± SD [kg/m2] | 24.24 ±2.95 | 21.1 ±3.73 | 0.04 |
| Disease duration, median (range) [years] | 5 (1–15) | 7.5 (4–14) | 0.06 |
| Duration of Raynaud’s phenomenon, median (range) [years] | 9.5 (1–30) | 11 (5–16) | 0.83 |
| mRSS, mean ± SD | 5.47 ±1.68 | 17.86 ±6.84 | 0.001 |
| Serum PPAR-γ level, mean ± SD [ng/ml] | 15.55 ±2.18 | 16.9 ±2.1 | 0.19 |
| hs-CRP level, mean ± SD [mg/l] | 1.4 ±0.37 | 1.59 ±0.43 | 0.29 |
BMI – body mass index, mRSS – modified Rodnan skin score, hs-CRP – high-sensitivity C-reactive protein.