Table 3.
Receiver operating characteristic (ROC) data for serum concentrations of metalloproteinases, inflammatory cytokines, and cartilage turnover markers in the study (PsA) group
| Paramter | MMP-1 | MMP-3 | IL-18 | IL-20 | YKL-40 | COMP |
|---|---|---|---|---|---|---|
| Cut-off value* | 5.90 | 14.30 | 40.18 | 57.40 | 34.40 | 1935.00 |
| Youden’s Index | 0.54 | 0.69 | 0.57 | 0.52 | 0.26 | 0.96 |
| AUC | 0.76 | 0.89 | 0.81 | 0.75 | 0.60 | 1.00 |
| P-value | 0.0007 | 0.0000 | 0.0001 | 0.0039 | 0.2635 | 0.0000 |
The values are given as ng/ml (MMP-1, MMP-3, COMP, YKL-40) and pg/ml (IL-18, IL-20).