Table 4.
The relationship between changes in the National Institutes of Health Stroke Scale (NIHSS) and the inflammatory factor changes
| NIHSS |
Changes in TNF-α (TNF-α after-
TNF-α baseline) |
Changes in CRP (CRP after-
CRP baseline) |
Changes in IL-6 (IL-6 after-IL-6
baseline) |
Changes in IL-1
β
(IL-1
β
after-
IL-1 β baseline) |
||||
|---|---|---|---|---|---|---|---|---|
|
Decreasing/unchanged
trend |
Increasing trend |
Decreasing/unchanged
trend |
Increasing
trend |
Decreasing/unchanged
trend |
Increasing
trend |
Decreasing/unchanged
trend |
Increasing
trend |
|
| Day 1 | 5.94 ± 3.45 | 6.96 ± 3.69 | 6.15 ± 4.50 | 6.87 ± 2.60 | 6.07 ± 3.50 | 6.76 ± 3.60 | 5.36 ± 2.30 | 6.96 ± 3.80 |
| Day 5 | 4.94 ± 3.57 | 5.03 ± 3.84 | 4.68 ± 4.50 | 5.25 ± 2.92 | 4.38 ± 3.20 | 5.26 ± 3.80 | 4.09 ± 2.50 | 5.31 ± 4.01 |
| Day 90 | 2.76 ± 2.60 | 3.07 ± 4.90 | 2.31 ± 3.36 | 3.45 ± 4.63 | 2.00 ± 2.30 | 3.36 ± 4.60 | 4.00 ± 6.40 | 2.50 ± 3.00 |
| P* | < 0.001 | 0.007 | < 0.001 | 0.001 | < 0.001 | 0.001 | 0.585 | < 0.001 |
Data are presented as mean ± standard deviation (SD)
IL-1β: Interleukin 1 beta; IL-6: Interleukin 6; CRP: C-reactive protein; TNF-α: Tumor necrosis factor-alpha; NIHSS: National Institutes of Health Stroke Scale
*
Repeated measures analysis of variance (ANOVA) test; the power analysis based on the result of table 4 indicated the power of > 95%