Table 2:
Baseline knee pain characteristics of Knee Pain Cohort
| Knee Pain Cohort (n=1221) | Vitamin D | Omega-3 Fish Oil | |||
|---|---|---|---|---|---|
| Active (n=591) | Placebo (n=630) | Active (n=595) | Placebo (n=626) | ||
| Knee Pain Frequency, n (%)* | |||||
| Never | 5 (0.4) | 2 (0.3) | 3 (0.5) | 2 (0.3) | 3 (0.5) |
| < 1 day/week | 62 (5) | 32 (6) | 40 (7) | 35 (6) | 27 (4) |
| 1–2 days/week | 136 (12) | 75 (13) | 61 (10) | 71 (12) | 65 (11) |
| 3–6 days/week | 240 (20) | 115 (20) | 125 (21) | 115 (20) | 125 (21) |
| Daily | 736 (62) | 350 (61) | 386 (64) | 354 (61) | 382 (63) |
| Prior Total Knee Replacement, n (%) | 176 (15) | 89 (15) | 87 (14) | 83 (14) | 93 (15) |
| Unilateral knee pain, n (%) | 821 (71) | 400 (71) | 421 (71) | 398 (70) | 423 (71) |
| Bilateral knee pain, n (%) | 338 (29) | 164 (29) | 174 (29) | 168 (30) | 170 (29) |
| Acetaminophen use, n (%) | |||||
| Never | 525 (49) | 243 (47) | 282 (51) | 245 (48) | 280 (51) |
| Occasionally | 380 (36) | 186 (36) | 194 (35) | 175 (34) | 205 (37) |
| Daily | 162 (15) | 83 (16) | 79 (14) | 94 (18) | 68 (12) |
| Nonsteroidal Anti-inflammatory medication use, n (%) | |||||
| Never | 269 (24) | 135 (25) | 134 (23) | 127 (23) | 142 (25) |
| Occasionally | 391 (35) | 192 (35) | 199 (35) | 199 (37) | 192 (33) |
| Daily | 462 (41) | 221 (40) | 241 (42) | 217 (40) | 245 (42) |
| Analgesics Including Opioids | |||||
| Never | 762 (69) | 364 (68) | 398 (70) | 371 (69) | 391 (68) |
| Occasionally | 171 (15) | 87 (16) | 84 (15) | 81 (15) | 90 (16) |
| Daily | 172 (16) | 86 (16) | 86 (15) | 82 (15) | 90 (16) |
| WOMAC Pain, mean, SD | 36.7 (18.7) | 36.2 (18.5) | 37.0 (18.8) | 37.2 (18.5) | 36.1 (18.8) |
| WOMAC Function, mean, SD | 36.7 (19.9) | 36.0 (19.8) | 37.5 (20.0) | 37.0 (20.2) | 36.4 (19.6) |
| WOMAC Stiffness, mean, SD | 44.3 (21.8) | 43.5 (22.1) | 45.0 (21.6) | 45.0 (22.5) | 43.7 (21.3) |
WOMAC; Western Ontario and McMaster Osteoarthritis Index. Scored 0–100, 100 worst.
*
Data from a baseline “knee pain questionnaire’ after eligibility established, thus some included participants now report having no or infrequent knee pain.