Figure S1.

Timeline of treatments relative to hospital admission date and DSM validation in an independent set of patients, related to Figure 1

(A) Timeline of treatments relative to hospital admission date. Dashed lines represent treatments with unknown start and/or end dates. Age and gender are listed next to each patient label. (B) Distribution of patient disease severity metric (DSM) grouped based on the WHO ordinal disease severity score of the CITE-seq cohort at the earliest time of PBMC sampling. The p value was computed using the Jonckheere trend test to assess the positive correlation between the WHO score and DSM. (C) Distribution of validation cohort disease severity metric (DSM) grouped by whether they were ever admitted to the ICU during the course of hospitalization for all patients (left) and only patients classified as Critical-Alive (right). Significance of difference between groups is determined by two-tailed Wilcoxon test.