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. 2020 Dec 4;7(1):299. doi: 10.18063/ijb.v7i1.299

Table 1.

Current efforts toward 3D composite bioprinting

Combined processes Main characteristics References
Phase transition through temperature gradient Extrusion printing Improve the mechanical properties and biocompatibility of the printed construction at the same time [21,22]
Ionic crosslinking Extrusion printing Provide more fabrication flexibility by controlling ion diffusion and material extrusion speed; perform cell printing under room temperature; effectively construct vessels like microchannels [27-30]
Electrohydrodynamics Extrusion printing Fabricate scaffolds with good mechanical properties and large scales, and the structure can mimic natural extracellular matrix on the micro-nano scale; effectively prepare the scaffolds with a multiscale pore structure [37,38,43-45]
Cell printing Hybrid additive/ subtractive manufacturing Construct vascularized bio constructs with certain mechanical strength and complex microstructure [62-64]
Physical field control Extrusion printing Improve printing flexibility, especially with environmentally responsive intelligent materials; regulate materials and cells in the printing process [65-69]