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. 2021 Feb 5;15:399–418. doi: 10.2147/DDDT.S293127

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© 2021 Gebreel et al.

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(A) In vitro release profiles of NFX from NFX-loaded PLGA NP-laden HPMC hydrogels in simulated tear fluid (pH 7.4), mean ± S.D., n = 3. (B) Ex vivo goat corneal permeation profiles of NFX from NFX-loaded PLGA NP-laden HPMC hydrogels in simulated tear fluid (pH 7.4), mean ± S.D., n = 3.

Abbreviations: NFX, norfloxacin; PLGA, poly(lactic-co-glycolic acid), NPs, nanoparticles; HPMC, Hydroxypropyl methylcellulose K4M.