Table 4.
Genetic Variations and Aeroallergens
Childhood (%) |
Adult (%) |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Pollen | Chenopodiaceous | Molds | Mites | Feather | Pollen | Chenopodiaceous | Molds | Mites | Feather | |
+2044 GG | 51 (42.85) | 21 (17.64) | 7 (5.88) | 17 (14.28) | 23 (19.32) | 49 (37.12) | 31 (23.48) | 6 (4.54) | 18 (13.63) | 27 (20.45) |
+2044 GA | 55 (42.63) | 23 (17.82) | 6 (2.32) | 19 (14.72) | 26 (20.15) | 36 (34.28) | 23 (21.90) | 4 (3.80) | 14 (13.33) | 31 (29.52) |
+2044 AA | 1 (50) | 0 | 0 | 0 | 1 (50) | 5 (38.46) | 3 (23.07) | 0 | 1 (7.69) | 4 (30.76) |
−590 CC | 58 (42.33) | 23 (16.78) | 10 (7.29) | 19 (13.86) | 27 (19.70) | 69 (38.76) | 39 (21.91) | 7 (3.93) | 21 (11.79) | 47 (26.40) |
−590 CT | 42 (41.58) | 17 (16.83) | 7 (6.93) | 15 (14.85) | 20 (19.80) | 19 (35.84) | 11 (20.75) | 2 (3.77) | 6 (11.32) | 15 (28.30) |
−590 TT | 5 (41.66) | 2 (16.66) | 1 (8.33) | 1 (8.33) | 3 (25) | 6 (31.57) | 4 (21.05) | 1 (5.26) | 2 (10.52) | 6 (31.57) |
Pollens and feather were the most common sensitization in AR patients in all type genotypes of IL4 (rs224325) and IL13 (rs20541) polymorphisms in the northwest of Iran.
AR, allergic rhinitis.