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. 2021 Feb 5;24(Suppl 1):S-35–S-42. doi: 10.1089/pop.2020.0256

Table 2.

Multivariate Logistic Regression of SARS-CoV-2 Serum IgG Positivity by NAAT Result, for Simultaneous IgG and NAAT Testing

Predictor Odds ratio estimates
(95% confidence limits)
P
NAAT Positive (n = 3868)
 State (NY/NJ/MA/RI/CT vs Other States) 10.3 (8.8, 12.0) <.0001
 Age in years (≥35 vs 2–34) 1.7 (1.4, 2.0) <.0001
 Sex (M vs F) 1.1 (0.9, 1.3) .4
 CCI* (≥1 vs None) 1.5 (1.3, 1.8) <.0001
NAAT Negative (n = 186,301)
 State (NY/NJ/MA/RI/CT vs Other States) 6.8 (6.4, 7.2) <.0001
 Age in years (≥35 vs 2–34) 1.1 (1.1, 1.2) <.0001
 Sex (M vs F) 1.0 (1.0, 1.1) .007
 CCI* (≥1 vs None) 1.2 (1.2, 1.3) <.0001

Logistic regression modeling IgG positive versus IgG negative with all predictors in the model, stratified by NAAT result.

*

Compare ≥1 CCI vs. no CCI.

CCI, chronic condition indicator; IgG, immunoglobulin G; NAAT, nucleic acid amplification testing; SARS-CoV-2, severe acute respiratory syndrome coronavirus-2.