Table 3. Risk Estimates (95% Confidence Intervals) for CHD Mortality in Men at the Index Age of 35.
| TC, mmol/L | Category: SBP/DBP, mmHg | Intermediate-Term Risk, % |
|||||
|---|---|---|---|---|---|---|---|
| 10-Year | 20-Year | 30-Year | 40-Year | 50-Year | LTR, % | ||
| < 5.7 | |||||||
| (< 220 mg/dL) | Normal: | 0.06 | 0.14 | 0.27 | 0.51 | 1.81 | 2.90 |
| < 130/< 80 | (0.00–0.14) | (0.02–0.25) | (0.11–0.42) | (0.28–0.73) | (0.97–2.37) | (1.55–3.71) | |
| High BP: | 0.00 | 0.12 | 0.5 | 1.27 | 2.66 | 3.93 | |
| 130–139/80–89 | (0.00–0.00) | (0.00–0.24) | (0.28–0.72) | (0.89–1.61) | (1.80–3.26) | (2.58–4.77) | |
| G1 hypertension: | 0.11 | 0.26 | 0.51 | 1.15 | 2.75 | 4.03 | |
| 140–159/90–99 | (0.00–0.33) | (0.00–0.55) | (0.18–0.83) | (0.72–1.54) | (1.93–3.34) | (2.76–4.80) | |
| G2–3 hypertension: | 0.00 | 0.79 | 1.22 | 2.01 | 4.20 | 5.11 | |
| ≥ 160/≥ 100 | (0.00–0.00) | (0.00–1.60) | (0.32–2.08) | (1.02–2.93) | (2.73–5.31) | (3.24–6.32) | |
| ≥ 5.7 | |||||||
| (≥ 220 mg/dL) | Normal: | 0.00 | 0.00 | 0.42 | 0.85 | 2.15 | 2.65 |
| < 130/< 80 | (0.00–0.00) | (0.00–0.00) | (0.04–0.79) | (0.18–1.45) | (0.23–3.51) | (0.12–4.32) | |
| High BP: | 0.00 | 0.10 | 0.33 | 1.07 | 2.65 | 3.70 | |
| 130–139/80–89 | (0.00–0.00) | (0.00–0.30) | (0.00–0.66) | (0.40–1.68) | (1.01–3.87) | (1.18–5.38) | |
| G1 hypertension: | 0.00 | 0.26 | 0.92 | 2.19 | 5.06 | 6.63 | |
| 140–159/90–99 | (0.00–0.00) | (0.00–0.63) | (0.29–1.52) | (1.19–3.08) | (2.73–6.66) | (3.39–8.63) | |
| G2–3 hypertension: | 0.00 | 0.35 | 1.77 | 3.49 | 5.76 | 7.73 | |
| ≥ 160/≥ 100 | (0.00–0.00) | (0.00–1.03) | (0.51–2.95) | (1.79–5.03) | (3.04–7.82) | (3.53–10.28) | |
A total of 44,761 Japanese men from 13 cohorts were included and the total number of observations was 636,489 person-years. Intermediate-term risks were defined as mortality-adjusted cumulative rates for 10-, 20-, 30-, 40-, and 50-year risk of CHD death. CHD, coronary heart disease; DBP, diastolic blood pressure; SBP, systolic blood pressure; LTR, lifetime risk; TC, total cholesterol.