Fig. 1. Anatomical mapping of genetic and epigenetic alterations in acral melanoma on the glabrous foot. Heel, forefoot, and hallux are yellow-colored and the centers of the lesions are plotted (n=52). Each dot is color-coded according to the mutation type (A) or PTEN promoter hypermethylation (B). (C) Both mutations and PTEN promoter hypermethylation are shown in each dot.