Table 2. Baseline clinical characteristics of acral melanoma patients.
| Variable | Total | Heel, forefoot and hallux | Midfoot and lesser toes | p-value |
|---|---|---|---|---|
| Patient | 52 (100.0) | 43 (82.7) | 9 (17.2) | |
| Median age, yr (range) | 65 (37~89) | 63 (37~89) | 67 (37~80) | 0.341 |
| Female sex | 26 (50.0) | 22 (51.2) | 4 (44.4) | 0.725 |
| BMI, kg/m2 (n=51) | 24.04±3.14 | 24.36±2.85 | 22.37±3.90 | 0.675 |
| ≤23 | 20 | 15 (35.7) | 5 (55.6) | |
| 23<BMI≤25 | 10 | 9 (21.4) | 1 (11.1) | |
| >25 | 21 | 18 (42.9) | 3 (33.3) | |
| Ulceration (n=43) | 0.071 | |||
| Yes | 17 | 16 (47.1) | 1 (11.1) | |
| No | 26 | 18 (52.9) | 8 (88.9) | |
| Thickness, mm (n=48) | 2.99±2.93 | 3.34±3.15 | 1.37±0.93 | 0.088 |
| Gene alteration | ||||
| BRAF (n=48) | 6 (12.5) | 5 | 1 | |
| NRAS (n=49) | 6 (12.2) | 5 | 1 | |
| TERT promoter (n=33) | 4 (12.1) | 4 | 0 | |
| KIT amplification (n=37) | 3 (8.1) | 3 | 0 | |
| PTEN promoter hypermethylation (n=48) | 12 (25.0) | 11 | 1 |
Values are presented as number (%), mean (range), mean±standard deviation, or number only.