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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Circ Arrhythm Electrophysiol. 2020 Dec 10;14(1):e009254. doi: 10.1161/CIRCEP.120.009254

Table 2.

Circadian Expression Parameters of Core Circadian Clock Transcripts in Human Failing Hearts. Circadian Expression Parameters of NR1D1, ARNTL, DBP, PER2, NFIL3 Transcript Expression in Two Sets of Failing Human Hearts. Acrophase reported in fractional Hours after Sunrise. % Rhythm; percentage of variation ascribed to a circadian expression with one 24 hour period. MAX-MIN; difference between the curve fitted peak and trough values. MESOR is the mean of the curve fitted values. NFIL3 analysis was not performed on set 1.

F HEART SET GENE ACROPHASE % RHYTHYM MAX-MIN MESOR
1 NR1D1 23.92 95.6 1.21 1.24
2 NR1D1 21.01 91.9 1.29 1.27
1 ARNTL 16.25 91.8 0.69 1.08
2 ARNTL 14.47 87.0 1.01 1.16
1 DBP 2.95 89.9 0.7 1.11
2 DBP 3.47 81.8 0.53 1.14
1 PER2 4.51 72.6 0.49 1.09
2 PER2 3.66 68.4 0.61 1.13
1 NFIL3 12.68 72.3 0.36 1.02
2 NFIL3 ND