Table 4.

Multivariate models for patients with RA with HOMA-IR >2.29 (dependent variable)

Predictor	β	OR	95% CI	P value
Multivariate model 1 using obesity covariate
Obesity (BMI>30)	1.795	6.01	1.94 to 8.66	0.002
Mean DAS28-CRP	1.021	2.77	1.29 to 5.99	0.009
IL-1β (pg/mL)	0.464	1.59	1.06 to 2.38	0.024
R2=0.352
Independent variables: age, sex, obesity (BMI>30), mean DAS28-CRP score, diagnostic delay, sedentary lifestyle
Multivariate model 2 using total fat mass covariate
Total fat mass (kg)	0.123	1.1	1.05 to 1.22	0.002
Mean DAS28-CRP	0.955	2.6	1.19 to 5.69	0.017
IL-1β (pg/mL)	0.456	1.57	1.06 to 2.34	0.023
R2=0.404
Independent variables: age, sex, fat mass, lean mass, mean DAS28, diagnostic delay, sedentary lifestyle

BMI, Body Mass Index; CRP, C reactive protein; DAS28, 28-Joint Disease Activity Score; HOMA-IR, homeostasis model assessment for insulin resistance; IL, interleukin; RA, rheumatoid arthritis.