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. Author manuscript; available in PMC: 2021 Feb 10.
Published in final edited form as: J Med Chem. 2018 Sep 19;62(4):1731–1760. doi: 10.1021/acs.jmedchem.8b01092

Figure 6.

Figure 6.

(A) Identification of compound 3–1b; (B) cocrystal structure of compound 3–1b with ALK (PDB ID: 2XBA, 1.95 Å). The kinase is depicted in yellow ribbons, and the hydrogen bonds are illustrated with blue dashed lines. Compound atoms are colored as follows: carbon, orange; nitrogen, blue; oxygen, red.