Skip to main content
. 2021 Jan 19;17(1):e1009195. doi: 10.1371/journal.ppat.1009195

Fig 1. Inoculation of K18-hACE2 mice results in lethal infection and virus shedding.

Fig 1

. a. Relative weight loss in mice after SARS-CoV-2 inoculation. The lines represent mean ± SEM. Wilcoxon matched-pairs rank test was conducted to compare weight differences between groups. b. Survival curves of mice inoculated with 104 or 105 TCID50 SARS-CoV-2, or 105 γ-irradiated SARS-CoV-2. c. Violin plot of viral load in nasal, oropharyngeal and rectal swabs with median as centre. Blue: 104 TCID50 (low dose animals, n = 6); red: 105 TCID50 (high dose animals, n = 6); green: 105 TCID50 γ-irradiated (control animals, n = 2); dotted line = limit of detection.