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. 2021 Jan 19;17(1):e1009195. doi: 10.1371/journal.ppat.1009195

Fig 5. Histologic features of nasal turbinates of SARS-CoV-2 infected mice.

Fig 5

a. Normal nasal turbinates from γ-irradiated SARS-CoV-2 inoculated control mouse lined by olfactory and respiratory epithelium. b. Absence of SARS-CoV-2 antigen immunoreactivity in respiratory and olfactory epithelial cells of low dose inoculated animal at 3 DPI. c. 3 DPI nasal turbinates lack inflammation but d. exhibit cytoplasmic immunoreactivity (brown) of respiratory epithelial cells for SARS-CoV-2 antigen. e. Higher magnification of respiratory epithelium. f. Higher magnification showing SARS-CoV-2 antigen immunoreactivity in ciliated respiratory epithelial cells. Magnification: a, b, c, d = 100 x; e, f = 400 x.