Table 1. Clinical characteristics of the HC, PD, and SWEDD groups.
| HC (141) | PD (304) | PD-SWEDD (13) | Other-SWEDD (37) | p-value | |
|---|---|---|---|---|---|
| Age at enroll | 60.7 ± 11.1 | 61.0 ± 9.6 | 59.8 ± 10.8 | 61.1 ± 9.9 | 0.97 |
| Gender (M: F) | 88: 53 | 199: 105 | 7: 6 | 23: 14 | 0.78 |
| Weight (kg) | 78.5 ± 15.8 | 81.3 ± 17.1 | 85.5 ± 11.2 | 85.5 ± 18.7 | 0.08 |
| Symptom duration (months) | 23.1 ± 22.3 | 13.8 ± 8.8 | 28.1 ± 33.8 | 0.20 | |
| Age of symptom onset | 59.0 ± 9.8 | 58.0 ± 11.3 | 58.6 ± 10.5 | 0.92 | |
| H&Y scales | 1.55 ± 0.51d | 1.50 ± 0.67 | 1.18 ± 1.00b | < 0.001 | |
| SCOPA-AUT, baseline | 6.4 ± 5.0b,c,d | 9.5 ± 6.8a,d | 14.9 ± 9.8a | 12.7 ± 8.4a,b | < 0.001 |
| SCOPA-AUT, 2yrs | 11.4 ± 7.1 | 14.8 ± 9.3 | 12.5 ± 7.3 | 0.20 | |
| MDS-UPDRS II, baseline | 1.5 ± 1.1b,c,d | 6.6 ± 4.1a | 5.3 ± 3.3a | 6.9 ± 4.6a | < 0.001 |
| MDS-UPDRS II, 2yrs | 8.7 ± 5.0 | 10.0 ± 7.9 | 9.1 ± 9.2 | 0.37 | |
| MDS-UPDRS III, baseline | 1.2 ± 2.1b,c,d | 20.3 ± 8.6a,d | 17.8 ± 9.1a,d | 12.8 ± 9.0a,b,c | < 0.001 |
| MDS-UPDRS III, 2yrs | 26.3 ± 11.1c,d | 20.2 ± 16.1b,d | 12.4 ± 13.0b,c | < 0.001 |
For a particular variable, values in superscripts indicate groups of statistically significant difference on post-hoc. Values represent:
a for HC,
b for PD,
c for PD-SWEDD, and
d for Other-SWEDD groups. Values are mean ± SD.