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. 2021 Feb 10;15(2):e0008861. doi: 10.1371/journal.pntd.0008861

Table 1. Demographic and other baseline characteristics of the dengue infection status (dengue-positive and non-dengue) among patients with non-malarial febrile illness identified in the health facility-based fever surveillance established in Lambaréné, Gabon in 2015–2016.

Characteristics Total (n = 682) Dengue-positive (n = 119) Non-dengue (n = 563) p-value
Mean age (SD) 9.15 (7.66) 8.96 (6.57) 9.19 (7.88) 0.766
Age group (years) 0.698
    1–4 233 (34.2) 40 (33.6) 193 (34.3)
    5–9 203 (29.8) 35 (29.4) 168 (29.8)
    10–14 105 (15.4) 19 (16.0) 86 (15.3)
    15–19 83 (12.2) 13 (10.9) 70 (12.4)
    20–24 43 (6.3) 11 (9.2) 32 (5.7)
    25–34 4 (0.6) 1 (0.8) 3 (0.5)
    35–55 11 (1.6) 0 11 (2.0)
Fever duration prior to visit 0.080
    1–2 days 226 (33.1) 29 (24.4) 197 (35.0)
    3 days 228 (33.4) 46 (38.7) 182 (32.3)
    4–7 days 228 (33.4) 44 (37.0) 184 (32.7)
Fever duration, entire illness 3.22 (1.24) 3.41 (1.24) 3.18 (1.23) 0.059
Temperature at presentation (SD) 38.31 (0.81) 38.39 (0.89) 38.29 (0.80) 0.211
Temperature at enrollment 0.514
    Below 38.5°C 509 (74.6) 86 (72.3) 423 (75.1)
    ≥ 38.5°C 173 (25.4) 33 (27.7) 140 (24.9)
Prev. dengue infection (self-report) 0 0 0 -
YF vaccination 473 (69.4) 85 (71.4) 388 (68.9) 0.589
Inpatients/Outpatients 116 (17.0)/566 (83.0) 24 (20.2)/95 (79.8) 92 (16.3)/471 (83.7) 0.313
Mean days of hospitalization among IPD patients (SD) 4.58 (1.35) 4.33 (1.74) 4.66 (1.21) 0.338
Female 321 (47.1) 49 (41.2) 272 (48.3) 0.157
Clinical diagnosis
    Suspected dengue 5 (0.7) 4 (3.4) 1 (0.2) < .001
    Non-dengue 677 (99.3) 115 (96.6) 562 (99.8)
    Viral syndrome (% of non-dengue) 247 (36.5) 40 (34.8) 207 (36.8)
    Malaria 236 (34.9) 44 (38.3) 192 (34.2)
    Diarrheal illness 99 (14.6) 15 (13.0) 84 (15.0)
    Bronchitis 39 (5.8) 4 (3.5) 35 (6.2)
    URI 13 (1.9) 2 (1.7) 11 (2.0)
    Otitis media 5 (0.7) 2 (1.7) 3 (0.5)
    Other 38 (5.6) 8 (7.0) 30 (5.3)
Signs and symptoms (presence)
    Rash 30 (4.4) 6 (5.0) 24 (4.3) 0.707
    Fatigue/weakness 248 (36.4) 53 (44.5) 195 (34.6) 0.041
    Headache 277 (40.6) 51 (42.9) 226 (40.1) 0.584
    Retro-orbital pain 25 (3.7) 9 (7.6) 16 (2.8) 0.013
    Neck pain 4 (0.6) 2 (1.7) 2 (0.4) 0.143
    Ear pain 7 (1.0) 2 (1.7) 5 (0.9) 0.436
    Breathing difficulty 19 (2.8) 4 (3.4) 15 (2.7) 0.675
    Nasal congestion 154 (22.6) 24 (20.2) 130 (23.1) 0.488
    Rhinorrhea 119 (17.5) 16 (13.5) 103 (18.3) 0.205
    Sore Throat 12 (1.8) 3 (2.5) 9 (1.6) 0.487
    Cough 376 (55.1) 61 (51.3) 315 (56.0) 0.350
    Sputum production 288 (42.2) 46 (38.7) 242 (43.0) 0.385
    Nausea & vomiting 289 (42.4) 49 (41.2) 240 (42.6) 0.771
    Diarrhea 222 (32.6) 35 (29.4) 187 (33.2) 0.421
    Constipation 36 (5.3) 10 (8.4) 26 (4.6) 0.093
    Abdominal pain 187 (27.4) 43 (36.1) 144 (25.6) 0.019
    Petechiae 6 (0.9) 1 (0.8) 5 (0.9) 0.960
    Loss of appetite 488 (71.6) 82 (68.9) 406 (72.1) 0.481
    Muscle pain 152 (22.3) 28 (23.5) 124 (22.0) 0.720
    Joint pain 154 (22.6) 28 (23.5) 126 (22.4) 0.785

°C: degree Celsius; IPD: Inpatient Department; OPD: Outpatient Department; SD: Standard Deviation; URI: Upper respiratory infection; YF: Yellow Fever.