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. Author manuscript; available in PMC: 2021 Feb 10.
Published in final edited form as: Br J Surg. 2019 Aug 23;106(13):1829–1836. doi: 10.1002/bjs.11293

Table 2.

Diagnostic value of nomograms for malignancy and invasiveness of intraductal papillary mucinous neoplasms in Eastern and Western cohorts

AUC Sensitivity Specificity BA Cut-off† Sensitivity Specificity BA
Malignancy Cut-off 0·37*
  Eastern 0·745
(0·608, 0·805)		 0·71
(0·59, 0·78)		 0·66
(0·63, 0·77)		 0·68
(0·63, 0·75)		 0·48 0·63
(0·58, 0·77)		 0·80
(0·68, 0·81)		 0·72
(0·65, 0·77)
  Western 0·856
(0·759, 0·917)		 0·64
(0·47, 0·76)		 0·92
(0·91, 1·00)		 0·78
(0·71, 0·86)		 0·29 0·71
(0·62, 0·88)		 0·88
(0·77, 0·92)		 0·79
(0·72, 0·87)
  Combined 0·776
(0·719, 0·818)		 0·68
(0·58, 0·74)		 0·74
(0·73, 0·83)		 0·71
(0·68, 0·77)		 0·35 0·71
(0·60, 0·75)		 0·74
(0·73, 0·83)		 0·72
(0·68, 0·77)
Invasiveness Cut-off 0·20*
  Eastern 0·736
(0·667, 0·801)		 0·69
(0·55, 0·79)		 0·69
(0·62, 0·75)		 0·69
(0·61, 0·75)		 0·20 0·69
(0·59, 0·82)		 0·69
(0·60, 0·73)		 0·69
(0·62, 0·75)
  Western 0·891
(0·808, 0·950)		 0·61
(0·45, 0·88)		 0·90
(0·82, 0·94)		 0·76
(0·66, 0·89)		 0·11 0·94
(0·66, 1·00)		 0·75
(0·71, 0·86)		 0·85
(0·71, 0·90)
  Combined 0·788
(0·731, 0·834)		 0·67
(0·57, 0·76)		 0·76
(0·71, 0·80)		 0·72
(0·66, 0·77)		 0·11 0·87
(0·72, 0·90)		 0·58
(0·54, 0·64)		 0·73
(0·65, 0·75)

Values in parentheses are 95 per cent confidence intervals.

*

Cut-off value that maximized balanced accuracy (BA) in previous study

†

cut-off value that maximized BA for each cohort. AUC, area under curve.