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Expression of DN-AMPK K57A suppressed synphilin-1-induced food intake and body weight gain in flies. Elav-Gal4;SP1 flies were crossed with UAS-AMPK-DN. (A) Food intake of various flies as indicated was observed at 1 to 5 days post-eclosion. (B) The body weight of various flies as indicated was measured at 10 days of age. There were 60 flies in each group. Data are mean±s.e.m. *P<0.05 (ANOVA followed by Tukey’s post-hoc test; significance between groups as indicated.
