Table 4.
Drug/extract | Dose (mg/kg) | Mean ± SD parasitemia (%) | % suppression of parasite | Mean survival time (days) |
---|---|---|---|---|
MeOH | 125 | 7.18 ± 0.73 | 56.29 | 10.50 ± 0.58 |
250 | 5.58 ± 0.39 | 66.05 | 11.25 ± 0.96 | |
500 | 4.03 ± 0.67 | 75.52 | 16.25 ± 0.96 | |
| ||||
EtOAc | 125 | 6.75 ± 0.31 | 59.02 | 11.00 ± 0.82 |
250 | 4.72 ± 0.19 | 71.27 | 12.40 ± 1.14 | |
500 | 4.04 ± 0.87 | 75.3 | 15.60 ± 1.52 | |
| ||||
CQ | 1.20 ± 0.23 | 92.59 | 28.25 ± 1.50 | |
| ||||
Vehicle | 16.45 ± 3.08 | 5.00 ± 0.82 |
∗The results are expressed as mean ± SD.