Extended Data Fig. 7. Expanded module enrichments and motif networks.

a–c, Enhancer module circuitry for heart (a), brain (b), and haematopoietic cells (c) expanding module subsets (Fig. 2d). From top to bottom, we show module centres for all samples in each group against all modules whose maximal inclusion lies in the group, motifs with over twofold enrichment (text: log₂FC), and GO enrichments for each module with tissue-category-specific enrichments. d, e, Snapshots of the motif-module network highlighting TEAD3 and HNF1A. Edges represent enrichments with log₂FC > = 1.5.