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. 2021 Feb 3;590(7845):300–307. doi: 10.1038/s41586-020-03145-z

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 12 — a, Shared enrichments with CAD for 56 of 803 traits sharing at least two enrichments with the top 20 enriched nodes of CAD. Matrix is diagonalized according to maximal enrichment (nominal p-value, only enrichments passing FDR <0.1% are shown). b, Extended GO terms for CAD lead SNPs in enriched nodes. All GO terms with at least -log₁₀q > 2enriched in less than 25% of nodes.