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. 2021 Jan 14;25(3):1342–1349. doi: 10.1111/jcmm.16239

FIGURE 1.

FIGURE 1

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) binds to angiotensin‐converting enzyme 2 (ACE2) and induces ACE2 shedding to produce soluble ACE2 in serum, which triggers an angiotensin II (Ang II)‐mediated inflammation response