Table 2.
Determinants for Health-related Quality of Life as measured with the Short-from 36 (SF-36), separately for the physical and mental component score
| Physical component score β (95% CI) | Mental component score β (95% CI) | |
|---|---|---|
| Sex female (ref: male) | − 2.521 (− 6.393 to 1.351) | 0.066 (− 4.182 to 4.315) |
| Age (years) | − 0.113 (− 0.248 to 0.023) | − 0.016 (− 0.165 to 0.133) |
| Tumor location, skull base (ref: convexity) | 2.832 (− 0.410 to 6.073) | 2.603 (− 0.974 to 6.180) |
| Tumor size before last intervention (mm) | 0.085 (− 0.017 to 0.187) | 0.023 (− 0.086 to 0.132) |
| Tumor size before study (mm) | − 0.235 (− 0.450 to − 0.020) | 0.20 (− 0.211 to 0.252) |
| Tumor growth on last MRI before study, yes (no) | 0.571 (− 1.479 to 2.626) | 0.816 (− 1.396 to 3.029) |
| Edema on last MRI before study, yes (ref: no) | − 2.798 (− 10.988 to 5.392) | 4.801 (− 4.077 to 13.678) |
| First resection, yes (ref: no) | 1.438 (− 5.564 to 8.439) | 3.072 (− 4.852 to 10.997) |
| First resection complications, yes (ref: no) | − 1.873 (− 5.596 to 1.851) | − 0.444 (− 4.648 to 3.760) |
| Second resection, yes (ref: no) | − 1.325 (− 8.290 to 5.640) | 1.610 (− 6.590 to 9.811) |
| Simpson grade first resection IV/V (ref: I–III) | − 1.241 (− 3.001 to 0.519) | 1.693 (− 0.216 to 3.602) |
| WHO Grade II (ref: I) | − 0.027 (− 6.657 to 6.603) | − 4.843 (− 11.988 to 2.301) |
| Radiotherapy, yes (ref: no) | − 2.950 (− 7.837 to 1.936) | − 3.327 (− 9.083 to 2.429) |
| Karnofsky performance score | 0.374 (0.170 to 0.578) | 0.388 (0.133 to 0.643) |
| Hand dominance, right (ref: left) | − 3.117 (− 7.694 to 1.460) | 1.168 (− 3.815 to 6.152) |
| Charlson Comorbidity Index | − 3.308 (− 4.624 to − 1.992) | − 0.021 (− 1.560 to 1.517) |
| Educational level (1: primary/secondary, 2: tertiary vocational, 3: academic) | 2.703 (0.540 to 4.867) | 0.762 (− 3.512 to 5.036) |
| Years since diagnosis | − 0.460 (− 0.500 to 0.410) | − 0.090 (0.720 to 0.400) |
Results marked in bold are significant
β Represent the decrease or increase in physical or mental component score. For continuous determinants this is per 1-point increase in the determinant, unless otherwise specified. For categorical variables a comparison is made with a reference category