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. 2021 Feb 10;11:3515. doi: 10.1038/s41598-021-82852-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Transmission EM of a single virus particle of SARS-CoV-2 at the surface of a Vero cell in an ultrathin plastic section (10 summed up digital slices of an electron tomogram). The section through the virus particle shows the main ultrastructural features of the virus which were manually highlighted by color: yellow = virus-enveloping membrane, red = surface projection (spike, peplomer; trimeric S protein), blue = ribonucleoprotein (N protein and RNA). Scale bar = 100 nm.