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Table of IC50 values from radio labeled kinase assay (n = 2 biologically independent experiments).
| Kinase: | SJF-0628 IC50 (nM) |
|---|---|
| ARAF | 0.27 |
| CRAF | 37.6 |
| BRAF | 5.80 |
| BRAF (V600E) | 1.87 |
| BRAF (V600A) | 1.06 |
| BRAF (V600D) | 2.68 |
| BRAF (V600K) | 0.49 |
| BRAF (G464V) | 9.18 |
| BRAF (G469A) | 0.98 |
| BRAF (K601E) | 7.84 |
| BRAF (L597V) | 16.0 |
