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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Prog Retin Eye Res. 2020 Aug 11;82:100897. doi: 10.1016/j.preteyeres.2020.100897

Figure 4.

Figure 4.

IOP homeostasis with constant pressure perfusion in human anterior segments (Acott et al., 2014; Acott et al., 2016). Perfusion at 1x pressure (8.8mm Hg) gives a normalized facility of 1.0 and doubling the pressure to 2x doubles the outflow immediately but the facility (~flow/pressure) does not change. However, over the next few days maintaining pressure at 2x, the resistance is decreased as the outflow system is attempting to compensate and the flow rate and facility increase. N=23 separate human anterior segments and significance was determined by one-way ANOVA with Dunnett’s Multiple Comparison Test.