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. 2021 Feb 10;16:27. doi: 10.1186/s11671-021-03475-5

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Exosomes alleviate pathological change and decrease apoptotic cells of placenta tissues in PE rats. a HE staining was utilized to test pathological features of placenta tissues in PE rats after exosome treatment. b TUNEL staining was implemented to determine apoptotic cells of placenta tissues in PE rats after exosome treatment. c Cell apoptosis rate was detected by TUNEL staining. n = 10, *p < 0.05 versus the normal group. ^#p < 0.05 versus the PE group. ^$p < 0.05 versus the PE + Exos-antagomir NC group. Measurement data were depicted as mean ± standard deviation, and comparisons among multiple groups were assessed by one-way ANOVA followed by Tukey’s test