Figure 3.

Pharmacodynamics of single- and repeat administration of MMF (A) and OKV-1001b (280 mg and 180 mg; B), as measured by ex-vivo mitogen stimulated T-lymphocyte proliferation. All pharmacodynamic results are expressed as percent inhibitions of pretreatment assay values for each dog. Boxes and horizontal bars denote interquartile range (IQR) and median percent inhibition, respectively. Whisker endpoints are equal to the maximum and minimum values below or above the median ± 1.5 times the IQR.