Table 1.
Genotypes of control and experimental flies and fly line names.
| Line name | Genotype |
|---|---|
| dprx5 | dprx5/ Da-GAL4, dprx5 |
| dprx3 | RNAi-dprx3/ Da-GAL4, dprx5 |
| DM | RNAi-dprx3, dprx5/ Da-GAL4, dprx5 |
| Control | +/ Da-GAL4, dprx5 |
| Appl DM | Appl-GAL4/ +; RNAi-dprx3, dprx5/ dprx5 |
| Appl Control | Appl-GAL4/ +; dprx5/ + |
| D42 DM | D42-GAL4/ +; RNAi-dprx3, dprx5/ dprx5 |
| D42 Control | D42-GAL4/ +; dprx5/+ |
DM – flies underexpressing dPrx3 with Da-GAL4 driver in dprx5 mutant background; Appl DM – flies underexpressing dPrx3 with Appl-GAL4 driver in dprx5 mutant background; D42 DM – flies underexpressing dPrx3 with D42-GAL4 driver in dprx5 mutant background. Controls were heterozygous flies carrying driver and transgene alleles. Since there was no significant difference in effects on lifespan and other fly characteristics between driver and transgene controls (17), we only present here the data for one of them, +/Da-GAL4, dprx5 obtained in the current experiments. Appl Control and D42 Control–corresponding driver controls for fly lines under-expressing Prxs with these drivers.