Table 2.

Mean life span of the double-mutant flies under-expressing dPrx3 in dprx5 null mutant background shown in Figure 1.

Males				Females
Line	Mean, days 1	% vs. control 2	p-value 3	Line	Mean, days 4	% vs. control 5	p-value 6
Da Control	63 63			Da Control	69 72
DM	20 19	31.7 30.2	<0.0001 <0.0001	DM	14 15	20.3 20.8	<0.0001 <0.0001
APPL Control	36 40			APPL Control	47 35
APPL DM	36 35	0.0 87.5	0.5035 0.0112	APPL DM	48 46	102.1 76.1	0.1293 0.0002
D42 Control	46 44			D42 Control	61 51
D42 DM	15 14	32.6 31.8	<0.0001 <0.0001	D42 DM	27 25	43.9 48.0	<0.0001 <0.0001

Columns 1 and 4 indicate mean life spans of two independent biological experiments; columns 2 and 5 indicate the percent changes in experimental groups vs. corresponding controls; columns 3 and 6 indicate the significance probabilities of comparisons of survival curves obtained by the log rank tests. Statistically significant differences are shown in bold.