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. 2021 Jan 28;10:621435. doi: 10.3389/fonc.2020.621435

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Copyright © 2021 Li, Li, Pan, Zhang, Xiang, Zhang, Sun, Yu, He and Hu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The cutoff value of FR⁺CTC level on prognosis and Kaplan-Meier curves of RFS and OS in NSCLC patients with different preoperative FR⁺CTC level. (A) The standardized statistic of integer valued log-rank scores as a function of the hypothetical cutpoint of FR⁺CTC level. The process obtains its maximum of 2.5 at 7.9 FU/3 ml as indicated by the dashed line. (B) RFS curve in patients with low (≤ 7.9 FU/3 ml) and high (> 7.9 FU/3 ml) FR⁺CTC level. (C) OS curve in patients with low (≤ 7.9 FU/3 ml) and high (> 7.9 FU/3 ml) FR⁺CTC level.