Table 2.
Neutralization of CHIKV strain 181/25 by CC3, CC3-hop, and variants.
| CHIKV sdAb | PRNT50 (ng/mL) | PRNT90 (ng/mL) |
|---|---|---|
| CC3 | 2.5 ± 0.07 | 31 ± 27 |
| CC3-hop | 5.4 ± 0.92 | 42 ± 22 |
| CC3-m1-hop | 12.3 ± 1.0 | 296 ± 21 |
| CC3-m2-hop | 4.6 ± 2.7 | 18 ± 2 |
| CC3-m3-hop | 3.9 ± 0.2 | 23 ± 2 |
| CC3-m4-hop | 3.8 ± 0.8 | 19 ± 16 |
| CC3-m5-hop | 4.4 ± 0.4 | 16 ± 2 |
| CC3-m6-hop | 8.9 ± 0.2 | 54 ± 14 |
| CC3-m7-Hop | 14.9 ± 3.5 | 146 ± 23 |
| CC3-m8-Hop | 21.1 ±2.3 | 209 ± 146 |
| CC3-m9-hop | 34.7 ± 6.8 | 149 ± 27 |
| CC3-m10-hop | 24.2 ± 2.0 | 169 ± 92 |
Each measurement was done in duplicate. In addition 2–3 biological replicates were performed; the average and standard deviation between sets of experiments are reported.