Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jan 28;12:636620. doi: 10.3389/fgene.2021.636620

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Wood, Eadsforth, Newman and O’Keefe.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Structural model of the human tri-snRNP in two different orientations. Left: An overview of the human tri-snRNP, including all RNA/protein components. Right: Rotated view of the model, exclusively showing the structural relationships between the disorder-associated U5 snRNP proteins discussed in this review. Other tri-snRNP RNA/protein components have been omitted for clarity. Model built using a previously reported 2.9Å cryo-electron microscopy (cryo-EM) structure of the human tri-snRNP (PDB: 6QW6) (Charenton et al., 2019).