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. 2021 Jan 28;12:636620. doi: 10.3389/fgene.2021.636620

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Copyright © 2021 Wood, Eadsforth, Newman and O’Keefe.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Functional and physical interactions between U5 snRNP proteins involved in retinal and craniofacial genetic disorders. A summary of the interactions between RP-associated U5 snRNP proteins and craniofacial disorder-associated U5 snRNP proteins discussed in this review. A double-headed arrow indicates an interaction between the two proteins. Blue labels describe the known function or hypothesized function of the interaction between the proteins. Genetic disorders associated with each protein are indicated in red along with the specific tissue type affected in each case. BMKS, Burn-McKeown syndrome; MFDGA; mandibulofacial dysostosis Guion-Almeida type; RP, retinitis pigmentosa. Figure created with BioRender.com.