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. 2021 Feb 8;6(8):2569–2612. doi: 10.1016/j.bioactmat.2021.01.030

Table 12.

The cell viability of antibacterial pure zinc and zinc alloy.

Alloy system Metal or alloy Cell Cell viability (Cell culturing time) [Ref.]
Pure Zn Zn EA.hy926 100% extract: cytotoxicity (1, 3, 5 days);
50% and 10% extracts: >90% (1, 3, 5 days)
[314]
Zn MC3T3-E1 100% extract: < 55% (1, 3, 5 days);
25% extract: 64.48% (1 day);
12.5% extract: > 90% (1, 3, 5 days)
[318]
MG-63 100% extract: < 55% (1, 3, 5 days);
25% extract: 87.30% (1 day);
12.5% extract: > 90% (1, 3, 5 days)
[318]
Ag-containing Zn–4Ag L929 100% extract: < 40% (1 day);
33.3% extract: approximately 40% (1 day);
16.7% and 10% extracts: approached 100% (1 day)
[323]
Saos-2 100% extract: < 40% (1 day);
33.3%, 16.7% and 10% extracts: approached 100% (1 day)
[323]
Cu-containing Zn-xCu (x = 1–4 wt%) EA.hy926 100% extract: cytotoxicity (1, 3, 5 days);
50% and 10% extracts: >90% (1, 3, 5 days)
[314]
Zn–4Cu EA.hy926 100% extract: only reaches 10–20% (1, 3, 5 days);
50% and 10% extracts: approaching 100% (1, 3, 5 days)
[322]
Zn–3Cu–Fe EA.hy926 100% extract: < 75% (3 days);
75% extract: 75–90% (3 days);
50% and 10% extracts: > 100% (3 days)
[316]
A7r5 75% and 100% extracts: < 75% (3 days);
50% extract: >75% (3 days);
10% extract: > 100% (3 days)
[316]
Zn–1Cu-0.1Ti MC3T3-E1 100% extract: < 55% (1, 3, 5 days);
25% extract: 82.74% (1 day);
12.5% extract: > 90% (1, 3, 5 days)
[318]
MG-63 100% extract: < 55% (1, 3, 5 days);
25% extract: 65.45% (1 day);
12.5% extract: > 90% (1, 3, 5 days)
[318]
Mg-containing Zn-0.8 Mg U-2 OS 75% and 100% extracts: < 20% (1 days);
50% extract: >80% (1 days);
10% extract: > approaching 100% (1 days)
[327]
L929 50%, 75% and 100% extracts: < 20% (1 days);
25% extract: > 100% (1 days)
[327]
Zn-0.5Al–Mg (0.1–0.5 wt%) MC3T3-E1 extraction medium: 102–108% (7 days) [320]