In the Thyroid Hormone Replacement for Untreated Older Adults with Subclinical Hypothyroidism (TRUST) study sites in the Netherlands and Switzerland, depressive symptoms were measured using the Geriatric Depression Scale (GDS-15). TSH indicates thyroid stimulating hormone.
aIn 87 participants from Ireland, depressive symptoms were measured using the Center for Epidemiologic Studies Depression 20-item scale (CESD-20); those participants were included in a secondary analysis on incidence of mild depression. In the UK, no depressive symptoms were measured.