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. 2021 Feb 4:1–14. doi: 10.1080/03007995.2021.1876005

Table 1.

Demographic data of patients on admission.

  Total (n = 257) Non-deterioration (n = 208) Deterioration (n = 49) p Value
Age, years 46 ± 17 43 ± 16 60 ± 13) <.001**
Sex
 Male 140 (54) 111 (43) 29 (11) .462
Length of stay 18 ± 10 17 ± 8 25 ± 16 <.001**
Current smoker 27 (10.5) 21 (10.1) 6 (12.2) .659
Signs and symptoms at admission
 Cough 138 (63.7) 106 (51) 32 (65.3) .07
 Sputum 81 (31.5) 61 (29.3) 20 (40.8) .119
 Myalgia 93 (36.2) 61 (29.3) 32 (65.3) <.001**
 Headache 34 (13.2) 25 (12) 9 (18.4) .238
 Rhinorrhea 17 (6.6) 13 (6.3) 4 (8.2) .748
 Dyspnea 43 (16.7) 25 (12) 18 (36.7) <.001**
Comorbidity
 Hypertension 53 (20.6) 33 (15.9) 20 (40.8) <.001**
 Diabetes 15 (5.8) 9 (4.3) 6 (12.2) .045*
 Coronary heart disease 16 (6.2) 10 (4.8) 6 (12.2) .091
 Cerebrovascular disease 8 (3.1) 5 (2.4) 3 (6.1) .18
 Chronic obstructive lung disease 2 (0.8) 1 (0.5) 1 (2) .346
 Carcinoma 6 (2.3) 3 (1.4) 3 (6.1) .085
 Chronic kidney disease 4 (1.6) 2 (1) 2 (4.1) .165
 Hepatitis B 12 (4.7) 9 (4.3) 3 (6.1) .705
 Tuberculosis 3 (1.2) 3 (1.4) 0 1
Medical history
 ACEI/ARB 26 (10.1) 16 (7.7) 10 (20.4) .008*
 CCB 32 (12.5) 21 (10.1) 11 (22.4) .018*
 Diuretic 3 (1.2) 2 (1) 1 (2) .471
 β-blocker 15 (5.8) 11 (5.3) 4 (8.2) .496
 Metformin 9 (3.5) 5 (2.4) 4 (8.2) .07
Vital signs at admission
 Respiratory rate 19 ± 2 19 ± 2 20 ± 2 <.001**
 Fever (temperature ≥ 37.3 °C) 156 (60.7) 116 (55.8) 40 (81.6) <.001**
 Pulse, beats per min 86 ± 13 86 ± 13 87 ± 14 .65
 Systolic blood pressure, mmHg 126 ± 18 124 ± 17 135 ± 19 .001**
 Diastolic blood pressure, mmHg 82 ± 11 82 ± 10 83 ± 14 .29

Summary statistics are means ± SD or n (%). p Values were calculated by Mann–Whitney U test, χ² test, or Fisher’s exact test, as appropriate.

Abbreviations. ACEI, Angiotensin-converting enzyme inhibitor; ARB, Angiotensin receptor blocker; CCB, Calcium channel blocker.

*p ≤ .05; **p ≤ .001.