Table 4.
Risk factors associated with in-hospital aggravation.
| c-Statistic | OR (95% CI) | p | |
|---|---|---|---|
| CRP (per 1 mg/L increase) | 0.833 | 1.053 (1.033–1.072) | <.001** |
| Procalcitonin (per 1 ng/L increase) | 0.799 | 1.008 (1.004–1.013) | <.001** |
| Age (per 10 years) | 0.786 | 2.043 (1.588–2.628) | <.001** |
| Albumin (per 5 g/L increase) | 0.782 | 0.291 (0.181–0.466) | <.001** |
| Lymphocyte count (per 1 × 109/L increase) | 0.721 | 0.202 (0.096–0.429) | <.001** |
| AST (per 10 U/L increase) | 0.692 | 1.513 (1.215–1.885) | <.001** |
| Myalgia | 0.687 | 4.820 (2.422–9.589) | <.001** |
| Temperature (per 1 °C increase) | 0.658 | 1.904 (1.310–2.769) | .001* |
| Systolic blood pressure (per 10 mmHg increase) | 0.653 | 1.393 (1.151–1.687) | .001* |
| HCO3 (per 1 mmol/L increase) | 0.630 | 0.787 (0.696–0.890) | <.001** |
| Platelet count (per 1 × 109/L increase) | 0.618 | 0.993 (0.987–0.999) | .021* |
| APTT (per 1 s increase) | 0.613 | 1.094 (1.017–1.176) | .015* |
| RBC (per 1 × 1012/L increase) | 0.626 | 0.407 (0.219–0.758) | .005* |
| Hypertension | 0.610 | 3.22 (1.586–6.537) | .001* |
| ALT (per 10 U/L increase) | 0.600 | 1.165 (1.008–1.346) | .039 * |
| Direct bilirubin (per 1 μmol/L increase) | 0.605 | 1.137 (1.021–1.267) | .019* |
| Creatinine (per 1 μmol/L increase) | 0.587 | 1.019 (1.008–1.030) | .001* |
| CCB | 0.561 | 2.544 (1.104–5.864) | .028* |
| ACEI/ARB | 0.550 | 2.595 (1.035–6.502) | .042* |
| Diabetes | 0.545 | 3.402 (1.145–10.103) | .027* |
| Metformin | 0.532 | 3.961 (1.020–15.368) | .047* |
Abbreviations. OR, Odds ratio; AST, Aspartate transaminase ; ALT, Alanine aminotransferase; ALB, Albumin; HCO3, Bicarbonate concentration; APTT, Activated partial thromboplastin time.
*p ≤ .05; **p ≤ .001.