Table 1.

Clinical characteristics before treatment at ICU.

Subject number	A*	B*	C*	1#	2#	3#	4#
AGE, GENDER	71 (M)	55 (F)	63 (M)	46 (M)	54 (F)	70 (F)	55 (F)
COMORBIDITIES					obese	COPD Gold III (cachectic)	COPD Gold II (Centrilobular emphysema)
SYMPTOMS	Feeling sick with fever	Fever (39-40°), headache, cough.	Fever, feeling sick.	Cough, fever, dyspnea, muscle pain, anosmia, loss of appetite.	Fever, dyspnea before admission.	Fever, cough, fatigue, shortness of breath. 08-12/05 admission for COPD (SARS-CoV-2 neg). 15-05 SARS-CoV-2 pos. 19-05 readmission for pneumonia.	Feeling sick, fever. 28/06/2020 tested SARS-CoV-2 negative. On 05/07/2020 tested again, this time SARS-CoV-2 positive.
DURATION OF FEVER IN DAYS	14	7	7	5	6	12	11
SORE THROAT	−	−	−	−	+	−	−
COUGH	+	+	−	−	+	+	−
SPUTUM PRODUCTION	+	−	−	−	−	−	−
FATIGUE	+	+	+	+	+	+	+
SHORTNESS OF BREATH	+	+	+	+	+	+	+
NAUSEA OR VOMITING	−	−	+	−	−	−	−

^*= conventional treatment only (pts A-C);

^#= add on-enoximone (pts number 1–4).