Table 2.
Standard care | Add-on enoximone | p value MW (one tailed) | ||||||
---|---|---|---|---|---|---|---|---|
BLOOD PARAMETERS COUNTS (ref. values) |
A* | B* | C* | 1# | 2# | 3# | 4# | |
Haemoglobin (6.8–9.3 mmol/L) | 6.9 | 6.8 | 8.1 | 9.0 | 6.5 | 7.5 | 6.2 | 0.4 |
C-reactive protein (0–10 mg/L) | 116 | 199 | 243 | 6 | 234 | 191 | 173 | 0.3 |
Albumin (30–50g/L) | 17 | 19 | 19 | 27 | 22 | 14 | 25 | 0.2 |
Bilirubin (µmol/L) | 13 | 8 | 18 | – | 5 | 8 | 6 | 0.1 |
D-dimer (0–0.5mg/L) | 2.1 | 0.21 | 2.8 | 0.54 | 0.33 | 1.3 | 0.47 | 0.3 |
Lactate (mmol/L) | 1.5 | 1.1 | 1.2 | 2.9 | 0.8 | 1.3 | 0.7 | 0.3 |
White blood cell, (4.0–10.0 × 109/L) | 23.7 | 8.5 | 13.8 | 5.3 | 9.7 | 11.0 | 4.4 | 0.1 |
Neutrophils, (2.0–6.0 × 109/L) | 9.0 | 7.6 | 12.5 | 2.8 | 7.9 | 9.7 | 3.6 | 0.2 |
Lymphocytes (1.0–3.5 × 109/L) | 12 | 0.7 | 0.7 | 1.5 | 1.4 | 0.8 | 0.8 | 0.3 |
Monocytes (1.0–3.5 × 109/L) | 0.86 | 0.13 | 1.00 | 0.51 | 0.32 | 0.43 | 0.12 | 0.2 |
Eosinophils (1.0–3.5 × 109/L) | 0.25 | 0.02 | 0.01 | 0.13 | 0.01 | 0.08 | 0.00 | 0.4 |
Platelet count (1.3–3.6 × 109/L) | 5.3 | 2.0 | 3.1 | 5.1 | 3.2 | 3.8 | 1.5 | 0.5 |
= conventional treatment only (pts A-C);.
= add on-enoximone (pts number 1-4).